LocalControl: Nonparametric Methods for Generating High Quality Comparative Effectiveness Evidence

Implements novel nonparametric approaches to address biases and confounding when comparing treatments or exposures in observational studies of outcomes. While designed and appropriate for use in studies involving medicine and the life sciences, the package can be used in other situations involving outcomes with multiple confounders. The package implements a family of methods for nonparametric bias correction when comparing treatments in cross-sectional, case-control, and survival analysis settings, including competing risks with censoring. The approach extends to bias-corrected personalized predictions of treatment outcome differences, and analysis of heterogeneity of treatment effect-sizes across patient subgroups.

Version: 1.1.0
Depends: R (≥ 3.0.0)
Imports: Rcpp, gss, cluster, lattice, stats, graphics
LinkingTo: Rcpp
Published: 2017-11-22
Author: Nicolas R. Lauve [aut], Stuart J. Nelson [aut], S. Stanley Young [aut], Robert L. Obenchain [aut], Melania Pintilie [ctb], Martin Kutz [ctb], Christophe G. Lambert [aut, cre]
Maintainer: Christophe G. Lambert <cglambert at unm.edu>
License: Apache License 2.0 | file LICENSE
NeedsCompilation: yes
SystemRequirements: C++11
Materials: README NEWS
CRAN checks: LocalControl results

Downloads:

Reference manual: LocalControl.pdf
Package source: LocalControl_1.1.0.tar.gz
Windows binaries: r-devel: LocalControl_1.1.0.zip, r-release: LocalControl_1.1.0.zip, r-oldrel: LocalControl_1.1.0.zip
OS X El Capitan binaries: r-release: LocalControl_1.1.0.tgz
OS X Mavericks binaries: r-oldrel: LocalControl_1.1.0.tgz
Old sources: LocalControl archive

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