Facilities for running simulations from ordinary differential equation (ODE) models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.
Version: | 0.6-1 |
Depends: | R (≥ 3.2.0) |
Imports: | utils, methods, digest, rex, dparser (≥ 0.1.7), brew, memoise, magrittr, Rcpp (≥ 0.12.3), inline, Matrix, R.utils |
LinkingTo: | dparser (≥ 0.1.7), Rcpp (≥ 0.12.3), RcppArmadillo (≥ 0.5.600.2.0) |
Suggests: | knitr, nlme, shiny, tcltk, testthat, devtools, covr, rmarkdown, SnakeCharmR, rSymPy, dplyr, tidyr, tibble, curl |
Published: | 2017-10-13 |
Author: | Matthew L. Fidler [aut], Melissa Hallow [aut], Wenping Wang [aut, cre] |
Maintainer: | Wenping Wang <wwang8198 at gmail.com> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
Copyright: | see file COPYRIGHTS |
URL: | https://www.r-project.org, https://github.com/nlmixrdevelopment/RxODE |
NeedsCompilation: | yes |
SystemRequirements: | GNU make |
In views: | Pharmacokinetics |
CRAN checks: | RxODE results |
Reference manual: | RxODE.pdf |
Vignettes: |
Introduction to RxODE RxODE Modeling Syntax |
Package source: | RxODE_0.6-1.tar.gz |
Windows binaries: | r-devel: RxODE_0.6-1.zip, r-release: RxODE_0.6-1.zip, r-oldrel: RxODE_0.6-1.zip |
OS X El Capitan binaries: | r-release: RxODE_0.6-1.tgz |
OS X Mavericks binaries: | r-oldrel: RxODE_0.6-1.tgz |
Old sources: | RxODE archive |
Reverse depends: | nlmixr |
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