RxODE: Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation (ODE) models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.

Version: 0.6-1
Depends: R (≥ 3.2.0)
Imports: utils, methods, digest, rex, dparser (≥ 0.1.7), brew, memoise, magrittr, Rcpp (≥ 0.12.3), inline, Matrix, R.utils
LinkingTo: dparser (≥ 0.1.7), Rcpp (≥ 0.12.3), RcppArmadillo (≥ 0.5.600.2.0)
Suggests: knitr, nlme, shiny, tcltk, testthat, devtools, covr, rmarkdown, SnakeCharmR, rSymPy, dplyr, tidyr, tibble, curl
Published: 2017-10-13
Author: Matthew L. Fidler [aut], Melissa Hallow [aut], Wenping Wang [aut, cre]
Maintainer: Wenping Wang <wwang8198 at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
Copyright: see file COPYRIGHTS
URL: https://www.r-project.org, https://github.com/nlmixrdevelopment/RxODE
NeedsCompilation: yes
SystemRequirements: GNU make
In views: Pharmacokinetics
CRAN checks: RxODE results

Downloads:

Reference manual: RxODE.pdf
Vignettes: Introduction to RxODE
RxODE Modeling Syntax
Package source: RxODE_0.6-1.tar.gz
Windows binaries: r-devel: RxODE_0.6-1.zip, r-release: RxODE_0.6-1.zip, r-oldrel: RxODE_0.6-1.zip
OS X El Capitan binaries: r-release: RxODE_0.6-1.tgz
OS X Mavericks binaries: r-oldrel: RxODE_0.6-1.tgz
Old sources: RxODE archive

Reverse dependencies:

Reverse depends: nlmixr

Linking:

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